Comparative studies between Japanese and Korean patients: Comparison of the findings of TA

http://www.springerlink.com/content/w76u247v7263350h/

Comparative studies between Japanese and Korean patients: Comparison of the findings of angiography,HLA-Bw52, and clinical manifestations

(1) Michiyoshi Yajima1 , Ryutaro Moriwaki1, Fujio Numano1, Young B. Park2 and Young D. Cho3 Department of Internal Medicine, Tokyo Medical and Dental University, Bunkyo-ku, 113 Tokyo, Japan

(2) Department of Medicine, Seoul National University Hospital, Seoul, Korea

(3) Department of Radiology, Kosin Medical Center, 600 Pusan, Korea

Summary

A Japan-Korea cooperative survey on Takayasu arteritis has shown some differences in the features between Japanese and Korean patients with this disease. In angiographic findings, Japanese patients more frequently had lesions at the aortic arch and/or its branches (58% of 75 cases), while, in Korean patients, the abdominal aorta is the site of relatively frequent lesions (30% of 112 cases). Higher occurrence ofHLA-Bw52 was found in Japanese patients in comparison with Korean patients (46% vs 15%). The presence ofHLA-Bw52, however, might have a close association with Takayasu arteritis in Korea as well as in Japan. The complications in 126 Japanese and 88 Korean patients were also compared. The complications occurring with higher frequency in Japanese patients were aortic regurgitation, ischemic heart disease, and visual disturbances, while, in Korean patients, the more frequent complications were renovascular hypertension as well as hypertension of some other etiology.

Key words Takayasu arteritis - Aortography - HLA-Bw52 - Aortic regurgitation

Source:

Journal: Heart and Vessels
Publisher: Springer Japan
ISSN 0910-8327 (Print) 1615-2573 (Online)
Issue: Volume 7, Supplement 1 / March, 1992
DOI
10.1007/BF01744553
Pages: 102-105
Subject Collection
Medicine
SpringerLink Date
Monday, June 20, 2005